SCIENCE AND INNOVATION

 
INNOVATION

We are relentless in our pursuit of advanced formulations of dietary supplements that offer more and better solutions to the growing need for healthy and nutritious wellness options.

With our patent-protected VESIsorb® formulations delivering optimal bioavailability of natural science-backed ingredients including CoQ10, QH Ubiquinol, Omega-3, Curcumin, Krill Oil, Vitamin D-3 and proprietary product formulas such as Ultimate Red Yeast Rice™, we take science-based natural ingredients & make them work better!

We offer an unmatched exclusive delivery system that optimizes our products for significant absorption and bioavailability in the body. We take science-based natural ingredients & make them work better!

BIO-ACTIVE BIOAVAILABILITY
The improvement of oral drug or natural bio-active bioavailability by this technology is broken down into three steps:
STEP 1
Formation of the colloidal delivery system. When mixed with an aqueous system (such as the GI-Lumen), this unique lipid-based formulation naturally forms a self-assembling colloidal delivery system containing solubilized bioactives. A colloidal droplet is typically less than 100nm in diameter and consists of a monolayer with the CoCo10 or other bioactives within its oil core.
STEP 2
Diffusion of the solubilized bioactives across the unstirred water layer.
STEP 3
Transfer of the solubilized CoQ10 or other bioactives to the absorptive surface of the intestine.
LATEST CLINICAL STUDIES

The peer-reviewed journal, “Alternative Therapies in Health and Medicine,” recently published the results of a double-blind study comparing the bioavailability of patented CoQsource® (coenzyme Q10 in a VESIsorb® formulation) Bio-Enhanced CoQ10 to that of other bio-enhanced formulations. The study, entitled, “Relative Bioavailability Comparison of Different Coenzyme Q10 Formulations with a Novel Delivery System,” appears in the March/April, 2009 issue, Volume 15, Number 2.

The graph below provides a vivid illustration of the difference in CoQsource® (the orange line) which is coenzyme Q10 in the VESIsorb® delivery system versus the three other “bio-enhanced” coenzyme Q10 products in plasma concentration levels over time. CoQsource® (coenzyme Q10 in the VESIsorb® delivery system) not only has higher plasma concentration levels after one hour, but continues to increase dramatically before reaching Cmax at about 4 hours. The plasma concentration of CoQsource® remains well above levels for the 3 other treatments throughout the 24 hour period.

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PRODUCT APPLICATION
The patented VESIsorb® delivery system is a naturally self-assembling colloidal droplet delivery system that has been clinically proven to increase absorption of nutritional supplement, functional food & beverage and cosmetic ingredients.
Product Advantages
  • The advantages of VESIsorb® delivery system go well beyond absorption and bioavailability.
  • The VESIsorb® system broadens the applications for certain bio-actives into food products, drink mixes, functional beverages and cosmetics.
  • The VESIsorb® system is easy to work with in production and effectively improves many production systems.
  • VESIsorb® has succeeded in addressing issues such as improved water solubility, oxidative stability, shelf life and uniformity of dispersion in the delivery medium.
THE DIFFERENCE BETWEEN MICELLES, LIPOSOMES AND VESISORB® COLLOIDAL DROPLETS
VESIsorb® vs. Micelles
Micelles are composed of a surfactant or surfactant mixture and the active substance to be solubilized within the center of the micelle. Compared to a micellar system, the VESIsorb® system contains lower amounts of surfactant (which is highly desirable) and high amounts of oil (lipophilic core/center where the active substance is dissolved) which is a significant advantage.
VESIsorb® vs. Liposomes
Liposomes are vesicles and composed of a phospholipid bi-layer membrane surrounding an aqueous core. Fat-soluble active substances can only be solubilized within the bi-layer membrane, thus the loading capacity is limited and lower compared to VESIsorb®.
VESIsorb® IS DESCRIBED AS A TECHNOLOGICALLY - ADVANCED DELIVERY SYSTEM
The colloidal droplet system is customized to each active or combinations of actives. Successful VESIsorb® formulations are optimized for droplet conversion performance using dynamic light scattering analysis.

The goal is 100% solubilized actives, in a completely homogeneous system with mean droplet size of less than 100nm. Meeting these criteria confirms that the VESIsorb® self-assembling colloidal droplet system is working.

What is also important to understand is that the system is not only built around the unique molecular characteristics of the bio-active but designed for optimal performance in the body.

The following photos are a VESIsorb® Coenzyme Q10 formulation compared to a leading brand that claimed the product was formulated for improved absorption:

PATENTED DELIVERY SYSTEMS
Advanced delivery system technologies allow OptiChoice® to adapt product formulations to a specific absorption and bioavailability need. This inures that any OptiChoice® product you choose will provide optimal utilization in the body and deliver the health benefits you are seeking.
Below are examples of the patented delivery system technologies we utilize in our products.
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VESISORB® Drug DELIVERY
Advanced delivery system technologies allow OptiChoice® to adapt product formulations to a specific absorption and bioavailability need. This inures that any OptiChoice® product you choose will provide optimal utilization in the body and deliver the health benefits you are seeking.
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DP TECHNOLOGY™
DPTechnology™ brings together a unique patented transferrin bound agent (peptide, protein, or compound) combined with a functional bioactive that is encapsulated into a liposome. DPTechnology™ has been used with Glutathione forming a natural Glutathione-MAPT protein resulting in more bioavailable Glutathione in the body.
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OSA™ EXTRACTION TECHNOLOGY
OSA™ is a patented extraction technology that captures the most potent and active constituents of the plant to deliver superior health benefits compared to standard products. The OSA™ technology has been applied to both our patented LeptiPURE™ and GymnePURE® products yielding a patented isolate and has been tested in clinical studies to be more bioavailable, safer and effective.

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VESISORB® VEDD DELIVERY SYSTEM
VESIsorb® VEDD delivery system is a patented and patent-pending micelle technology that has been shown to improve the oral bioavailability of water insoluble compounds. VEDD is a natural water soluble Vitamin E Derivative Dimer technology. Combined with water insoluble compounds like OmegaChoice® Vegan Omega-3 or D-Sorb™ Vitamin D-3, delivers water soluble vegetarian DHA Omega-3 or vitamin D-3 powders and soft gel capsules.
"It's not what you take, it's what your body absorbs."